What Is The Difference Between Nucleoside And Nucleotide
Olivia Luz
Nucleotides are built of a nitrogenous base a sugar and a phosphate group when it comes to chemical composition.
Nucleosides and nucleotides are a similar type of molecules that differ by a slight structural change. A nucleotide consists of a nitrogenous base a sugar ribose or deoxyribose and one to three phosphate groups. The key difference between nucleotide and nucleoside is that the nucleotide contains a phosphate group while the nucleoside lacks a phosphate group. More sources and references.
A nucleoside is formed by the attachment of a base to position of sugar. Difference between nucleotide and nucleoside with examples nucleoside is a structural sub unit of nucleic acids the heredity controlling component of all living cells consisting of a molecule of sugar linked to a nitrogen containing organic ring compound. A nucleoside consists of a nitrogenous base covalently attached to a sugar ribose or deoxyribose but without the phosphate group. On the other hand all the three basic components of nucleic acids i e pentose sugar phosphoric acid and base are present in a nucleotide.
Nucleosides are usually obtained by chemical or enzymatic decomposition of nucleic acids. However these nucleic acids are quite important in the body of living organisms. The core difference between nucleoside and nucleotide is the presence of the phosphate group. Nucleosides are built of a nitrogenous base and a sugar however without the phosphate group when it comes to chemical composition.
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The key difference between nucleoside and nucleotide reverse transcriptase inhibitors is that nucleoside reverse transcriptase inhibitors should be phosphorylated by host s cellular kinases while nucleotide reverse transcriptase inhibitors do not need to undergo initial phosphorylation.
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